Animal models, especially mice, are the most common way to study the effects of medicine thoroughly before attempting human clinical trials. Commonly used mice for immunological studies are the C57BL/6 (abbreviated B6) and BALB/c (abbreviated Balbc) mouse strains. C57BL/6 Mouse Strain BMDC in Immunology The C57BL/6 mouse strain is a popular choice for immunology researchContinue reading “Mice: C57BL/6 (B6) and BALB/c (Balbc)”
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Th1 and Th2 Immune Response
To understand the Th1 and Th2 responses, we must first understand the basis of these immune responses. Cytokines are the hormonal messengers responsible for most of the biological effects in the immune system. These messengers can be functionally divided into two groups: those that are pro-inflammatory and those that are anti-inflammatory but promote allergic responses.Continue reading “Th1 and Th2 Immune Response”
Making Bone Marrow-Derived Dendritic Cell (BMDC) Culture
Bone Marrow-Derived Dendritic Cells (BMDC) are potent antigen-presenting cells (APC) that have the unique capacity to initiate primary immune responses. BMDC is used in clinical studies to induce immunity against infectious diseases and malignant cells. This BMDC immunostimulatory capacity makes them attractive candidates for modulating immunity against pathogens, including viruses and bacteria, and also againstContinue reading “Making Bone Marrow-Derived Dendritic Cell (BMDC) Culture”
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